Centromere Dynamics and Chromosome Evolution in Marsupials
نویسندگان
چکیده
منابع مشابه
Centromere dynamics and chromosome evolution in marsupials.
The eukaryotic centromere poses an interesting evolutionary paradox: it is a chromatin entity indispensable to precise chromosome segregation in all eukaryotes, yet the DNA at the heart of the centromere is remarkably variable. Its important role of spindle attachment to the kinetochore during meiosis and mitosis notwithstanding, recent studies implicate the centromere as an active player in ch...
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Marsupials typically possess very large, distinctive chromosomes that make them excellent subjects for cytogenetic analysis, and the high level of conservation makes it relatively easy to track chromosome evolution. There are two speciose marsupial families with contrasting rates of karyotypic evolution that could provide insight into the mechanisms driving genome reshuffling and speciation. Th...
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To generate a model of mammalian karyotype evolution and to extend our knowledge of the evolutionary relationships of mammals, it is helpful to deduce ancestral chromosomal arrangements. Of particular interest would be a global comparison among the 3 major extant groups of mammals, since this would reveal the most ancient arrangements of the mammalian genome and allow us to follow chromosomal r...
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The organization of chromosomes into territories plays an important role in a wide range of cellular processes, including gene expression, transcription, and DNA repair. Current understanding has largely excluded the spatiotemporal dynamic fluctuations of the chromatin polymer. We combine in vivo chromatin motion analysis with mathematical modeling to elucidate the physical properties that unde...
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Marsupials have been known to European biologists almost since the discovery of theAmericas at the end of the fifteenth century; properly classifying them took some time. While the novelty of the opossum’s pouch was instantly appreciated, no special position outside the then-usual classification of mammals seemed needed. Nor could this easily have been done: most arrangements of the time were r...
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ژورنال
عنوان ژورنال: Journal of Heredity
سال: 2004
ISSN: 0022-1503,1465-7333
DOI: 10.1093/jhered/esh063